Endocrine Abstracts

Introduction: Tolvaptan, a selective vasopressin 2 receptor antagonist is proving beneficial in managing hyponatremia secondary to SIADH.Case report: A 75-year-old male with history of traumatic SAH developed hyponatremia secondary to SIADH. He had multiple admissions with symptomatic hyponatremia. His sodium level kept dropping despite putting on fluid restriction and trial of sodium chloride tablets. He was started on Tolvaptan 7.5 once weekly initiall...

Introduction: Polycystic Ovary Syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, with important long term health consequences such as higher chance of developing Type 2 diabetes, reduced overall wellbeing with poor quality of life. Such a common condition is mainly treated and investigated in the primary care setting.We therefore set out to see if the randomized controlled trials (RCT) represent the most common setting of care.<p class="abstex...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Background: Considering the high prevalence of metabolic and mental health issues associated with PCOS, it is important to screen for these routinely in clinic. We aimed to implement a standard approach to ensure we do this in our specialist PCOS clinic.Methods: We introduced a standard ‘PCOS clinic pack’ which included the following documents and data collected for analysis1. Checklist for doctors to e...

Background: Nice guideline recommends using TSH receptor antibody as a tool for classification of hyperthyroid patients; and considering technetium scanning of the thyroid gland if TRAbs are negative. Early diagnosis of TED is also essential for treatment to be effective. The most common way to assess the severity of TED is to use the Clinical Activity Score (CAS) 7-point scale.Objectives: We aimed to evaluate if hyperthyroid patients are classified corr...

Background: Adrenal crisis is a potentially life-threatening situation which can affect any patient with adrenal insufficiency (AI). Patients with AI and healthcare professionals looking after them should know the sick day rules and when and how to use parenteral hydrocortisone. Patient stories and feedback from patients with AI indicated low standards locally. We therefore aimed to empower patients through education and provide them with a hydrocortisone emergency kit.<p ...

Case history: Thyrotoxic periodic paralysis (TPP) which was first described in 1902 is characterised by episodes of painless muscle weakness, hypokalaemia and thyrotoxicosis without any total body potassium deficit. It predominantly affects people of Asian descent between 20 and 40 years old with a 2 percent incidence compared to 0.2 percent in non-Asian descent. The pathogenesis of TPP is related to an increase Na+/K+-ATPase activity in the skeletal muscle leading to an influ...

Background: Multimorbidity, presence of 2 or more chronic conditions, is a growing issue for patients as well as health systems. Reported prevalence of multimorbidity in females in a UK study was 23%. Presence of an additional chronic condition adds challenges to an existing condition. The difficulties of living with polycystic ovary syndrome (PCOS) have been well described both in terms of dealing with the symptoms as well as the potential metabolic and men...

Background: Multimorbidity, presence of 2 or more chronic conditions, is a growing issue for patients as well as health systems. Reported prevalence of multimorbidity in females in a UK study was 23%. Presence of an additional chronic condition adds challenges to an existing condition. The difficulties of living with polycystic ovary syndrome (PCOS) have been well described both in terms of dealing with the symptoms as well as the potential metabolic and men...

Background and aims: Polycystic Ovary syndrome (PCOS) is a common, lifelong condition. Its associated symptoms have been linked with psychological consequences, but less attention has been given to the daily implications of living with the condition. We aimed to explore women’s experiences of living with PCOS, including a specific focus on practical implications and methods of providing support such as structured group-based patient education.Method...